I use the 2004 Contractor Edition of Quickbooks for all my inhouse accounting. It works great. I also run a network drive for backups. Mostly its so I can access technical manuals from anywhere, but I also backup my accounting onto it.
Yesterday my main accounting computer crashed. Actually I am sure its just a Windows error as I can boot with one of my special tools CDs and explore the file structure. Windows just keeps rebooting over and over. Anyway, I grabbed a spare computer off the shelf, loaded my Quickbooks, and restored from my backup in less than 20 minutes. I was able to invoice the jobs I needed to, check data, and do a bank deposit, and I was good to go. I bought a couple reconditioned XP Pro work stations on the cheap last year for spares and front office work stations when I realized how much Vista sucks, and that some of my critical applications won't run on Vista.
Now I just need to figure out how to get this "new machine" configured for my dual head monitor card.
I have my Quickbooks setup to do an on drive backup everytime it shuts down, and a daily early AM backup to my network drive. Its a standalone network drive, although I imagine if you have enough faith in Windows you could just use another PC for it, and set it to auto reboot every day to prevent the Windows memory error from locking it up.
I would sure like to figure out how to get that autobackup on shutdown to be routed to my network drive or another external drive, but there does not seem to be anyplace to configure that.